Incumbent Republican William Timmons faces Democrat Courtney McClain in South Carolina’s 4th District on November 3, 2026, in a seat rated Solid or Safe Republican by nonpartisan forecasters with an R+11 Partisan Voter Index. Timmons secured the GOP nomination in the June primary by a wide margin, while McClain advanced unopposed on the Democratic side. The district’s consistent Republican voting history and limited crossover support keep the contest noncompetitive, with models projecting a Republican margin near 19 points. Trader pricing in the 10–20 point Republican victory buckets reflects this baseline, though national midterm dynamics, turnout shifts among key voting blocs, or late campaign spending could narrow or widen the final result. Resolution hinges on certified vote totals.